Abstract W P330: Antithrombotic Treatment Patterns Among Patients with Non-Valvular Atrial Fibrillation in a Managed Care Setting

Background: Antithrombotic therapy (warfarin or aspirin (ASA)) has been recommended to reduce the risk of stroke in patients with NVAF. The purpose of this study was to describe antithrombotic treatment patterns and baseline differences for managed care patients newly diagnosed with NVAF. Methods: Patients age ≥18 years and newly diagnosed with NVAF (index date) were identified between 01/01/2006_12/31/2011 within Kaiser Permanente Southern California databases and followed until 12/31/2012. Prescriptions, anticoagulation clinic information, and international normalized ratio (INR) monitoring were used to create 4 treatment groups: 1) continuous warfarin, 2) discontinuous warfarin (≥1 treatment gap >80 days), 3) ASA only, and 4) no antithrombotic therapy. Descriptive statistics were used to compare groups. Results: A total of 28,776 patients were identified with median follow up of 2.5 years. Among the 81% of patients (23,297) with ≥1 CHADS2 risk factor for stroke at baseline: 27.4% were continuously trea...