Oral Manifestations in Apert’s syndrome: From Diagnosis to Treatment

Apert’s syndrome, better known as acrocephalosyndactyly, is a pathology that is associated with the Fibroblast Growth Factor Receptor 2 (FGFR2) gene mutation. However, some cases may be related to new sporadic mutations associated with elevated paternal age. Objective: The main objective of this study is to show the oral manifestations, such as maxillary hypoplasia, in which compression of the dental sac is observed, causing irregular positioning of the teeth and marked thickening of the alveolar process, gingival hypertrophy, high susceptibility to cavities proliferation and dental breakdown, as well as their treatments. Methodology: The method used was referenced from scientific articles and clinical case studies. Results and Discussion: It was possible to observe that the occurrence of this syndrome is extremely rare (case for one hundred thousand to one hundred and sixty thousand births). In addition, it became clear that a higher incidence of bacterial plaque in patients with the syndrome due to poor oral hygiene, which is a consequence of syndactyly – because it is a limiting motor factor.