Preparations anti-viral potential of 5'-phosphonate modified azidothymidine

Marina K. Kukhanova,Anastasiya Lvovna Khandajinskaya,Maxim Vladimirovich Yasko,Elena A. Shirokova,Alexander V. Shipitsyn,Andrey G. Pokrovsky

Preparations anti-viral potential of 5'-phosphonate modified azidothymidine

2005

Marina K. Kukhanova
Anastasiya Lvovna Khandajinskaya
Maxim Vladimirovich Yasko
Elena A. Shirokova
Alexander V. Shipitsyn
Andrey G. Pokrovsky

5'-Phosphonates of AZT with the following general formula: ** ** Formula wherein R is selected from ClCH2-, ICH2-, HOCH2-, CH3OCH2- or H2NC (O) -, for use in methods for treating HIV .

Keywords:

Phosphonate
Biochemistry
Organic chemistry
Chemistry
human immunodeficiency virus
Stereochemistry

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