ФЛУОРЕСЦЕНТНЫЙ ЗОНД НА ОСНОВЕ ШИФФОВА ОСНОВАНИЯ 1,8-НАФТАЛИМИДА ДЛЯ ИОНА МЕДИ(II): СИНТЕЗ, ХАРАКТЕРИСТИКА И ПРИМЕНЕНИЕ

A novel fluorescent probe, 2-allyl-6-((2-((2-hydroxy-5-nitrobenzylidene)amino)ethyl)amino)-1Hbenzo[de]isoquinoline-1,3(2H)-dione (ABID), based on naphthalimide-Schiff base, has been designed and synthesized for the monitoring of Cu 2 + ions. In solution (DMSO/ HEPES, 1:1, v/v, pH 7.4), ABID displayed fluorescence quenching towards Cu 2 + ions over other important metal ions. A good linearity with a correlation coefficient (R 2 ) of 0.99 validated that probe ABID could be used to detect Cu 2 + ions in 0.5–5.0 μM concentrations. The limit of detection of ABID for Cu 2+ could reach at 3.4×10 –7 M level, and the quenching constant (K SV ) of ABID towards Cu 2 + was calculated to be 3.4×104 M – 1 . The 2:1 stoichiometry and the binding mode between ABID and Cu 2 + were studied by a Job plot and UV-Vis and fluorescence titration. Additionally, ABID was successfully employed to monitor Cu 2+ in the Yellow River and tap water samples.