Severe hemolysis and vasoclusive crisis due to COVID-19 infection in a Sickle Cell Disease patient improved after Red Blood Cells exchange

As the clinical course of COVID-19 infection in SCD patients is not clear, close monitoring is essential. We emphasize that RBC exchange should be offered early to avoid possible deterioration. We present a case of COVID-19 infection in a SCD patient causing severe hemolysis, that improved after RBC exchange.