L-755,807, A new non-peptide bradykinin binding inhibitor from an endophytic Microsphaeropsis sp.
1996
Abstract A new metabolite, L-755,807, 1 , was isolated from an endophytic Microsphaeropsis sp. in the course of searching for a bradykinin binding inhibitor. The structure of 1 , including relative stereochemistry, was determined. 1 showed an IC 50 of 71 μM in 3 H-bradykinin binding to a cloned human B 2 receptor.
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