Clinical value of surgical treatment in hepatic metastasis in patients with epithelial ovarian cancer
2014
Objective To discuss the clinical value of surgical treatment of hepatic metastasis in patients with epithelial ovarian cancer. Methods A retrospective review of clinical data of 25 ovarian carcinoma patients was conducted, and all of them had undergone hepatic resection for hepatic metastasis in Peking Union Medical Collage Hospital from July 2002 to July 2012. Results By liver resection for hepatic metastasis of epithelial ovarian cancer, and 23 out of 25 patients (92%) had optimal tumor debulking resulting to reduce residue foci less than 1cm in diameter, thus rendering suboptimal surgery to reach optimal cytoreductive surgery. Six patients, in whom hepatic metastasis was found, and chemotherapeutic effect was poor, attained optimal primary cytoreductive surgery by resection. Univariate analysis showed that the site and number of hepatic lesions, the presence of metastasis at other sites and the thoroughness of removal of hepatic metastatic lesions were significantly related with postoperative prognosis. The Cox multivariate proportional hazard model indicated that independent prognostic factors were whether there is metastasis in other organs and the thoroughness of removal of hepatic lesions. Conclusion Improved optimal cytoreduction surgery by resection of metastatic epithelial ovarian cancer to liver will improve the prognosis.
DOI: 10.11855/j.issn.0577-7402.2014.08.09
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