Application of enteral nutrition sequential therapy in patients with severe cerebrovascular disease

Objective To explore the role of clinical application of enteral nutrition sequential therapy in early enteral nutrition support by comparison with enteral nutrition non-sequential therapy in critically ill patients with cerebrovascular diseases. Methods A total of 62 patients were randomly (random number) divided into sequential group and conventional (non-sequential) grouThe comparisons of tolerance for enteral nutrition support, levels of prealbumin, the mechanically ventilated time and mortality rate in 28-day between two groups were carried out. Results The tolerance of sequential group was superior to that of conventional group (P<0.05). The higher level of prealbumin and the shorter mechanical ventilation time were observed in sequential group compared with conventional group (P<0.01). Compared with conventional group, the patients in sequential group had lower mortality rate in 28 days (P<0.05). Conclusions Sequential therapy is beneficial to the implementation of early enteral nutrition support in patients with severe cerebrovascular disease, reducing the nutritional adverse events, and improves the prognosis. Key words: Sequential therapy; Early enteral nutrition; Severe cerebrovascular disease