Transdermal delivery of fluvastatin sodium via tailored spanlastic nanovesicles: mitigated Freund's adjuvant-induced rheumatoid arthritis in rats through suppressing p38 MAPK signaling pathway

Shahira F. El-Menshawe,Mohamed M. Nafady,Heba M. Aboud,Rasha M. Kharshoum,Asmaa Mohammed M Hussein Elkelawy,Doaa S. Hamad

Transdermal delivery of fluvastatin sodium via tailored spanlastic nanovesicles: mitigated Freund's adjuvant-induced rheumatoid arthritis in rats through suppressing p38 MAPK signaling pathway

2019

Shahira F. El-Menshawe
Mohamed M. Nafady
Heba M. Aboud
Rasha M. Kharshoum
Asmaa Mohammed M Hussein Elkelawy
Doaa S. Hamad

AbstractThe current study aimed to encapsulate fluvastatin sodium (FVS), a member of the statins family possessing pleiotropic effects in rheumatoid arthritis (RA), into spanlastic nanovesicles (SN...

Keywords:

Rheumatoid arthritis
Pharmacology
P38 MAPK Signaling Pathway
Transdermal
Fluvastatin Sodium
Freund's adjuvant
Biochemistry
Materials science
p38 mitogen-activated protein kinases

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