Does the use of an orthotic increase comfort, decrease injury and improve running performance?

Background: Running is a widely accessible sport with millions of participants in the UK alone. Whilst running has been recognised to have significant health benefits, it does come with a risk of injury. Running-related injuries (RRIs) are seen more commonly in novice runners compared to athletes. Currently, there is ongoing debate as to what is the major cause of RRIs with some suggesting it is down to the differences in striking pattern. RRIs cause a substantial economic burden. There is no clear guidance as to whether the use of an orthotic truly prevents injury and improves running performance.