Resuscitative endovascular balloon occlusion of the aorta (REBOA) in a pediatric swine liver injury model: a pilot study

Abstract Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) has not been studied in children. We hypothesized that REBOA was feasible and would improve hemorrhage control and survival time, compared to no aortic occlusion, in a pediatric swine liver injury model. Methods Pediatric swine were randomized to Zone 1 REBOA or no intervention (control). Piglets underwent a partial liver amputation and free hemorrhage followed by either REBOA or no intervention for 30 min, then a damage control laparotomy and critical care for 4 h. Results Compared to control piglets (n = 5), REBOA piglets (n = 6) had less blood loss (34.0 ± 1.6 vs 61.3 ± 2.5 mL/kg, p  Conclusion In pediatric swine, 30 min of REBOA is feasible, decreases blood loss after liver injury and may improve survival. Level of Evidence. Level 1.