An efficient approach to prepare boronate core–shell polymer nanoparticles for glycoprotein recognition via combined distillation precipitation polymerization and RAFT media precipitation polymerization

Stimuli-responsive core–shell nanoparticles, with 3-acrylamidophenyl boronic acid (APBA) as the functional group, were synthesized via combined distillation precipitation polymerization and RAFT media precipitation polymerization. The well-defined boronic acid-polymer branch on the nanoparticle surface displayed high binding capacity and good selectivity towards cis-diol-containing molecules.