Inhibin/activin-betaC subunit does not represent a prognostic parameter in human endometrial cancer.

Introduction Inhibins, dimeric peptide hormones composed of an α subunit and one of two possible β subunits (betaA or betaB), exhibit substantial roles in human reproduction and in endocrine-responsive tumors. Recently, two novel inhibin-beta subunits, defined as betaC and betaE, have been identified in humans. However, the prognostic significance and clinical implications of the novel inhibin-betaC subunit in endometrial cancers is still quite unclear.