Enantioselective Syntheses of 1,4-Pentadien-3-yl Carbinols via Brønsted Acid Catalysis

An asymmetric addition of substituted 1,3-pentadienylboronates to aldehydes via Bronsted acid catalysis is reported. Under the developed conditions, a variety of synthetically useful 1,4-pentadien-3-yl carbinols were obtained in good yields with high enantioselectivities in the presence of a catalytic amount of a chiral phosphoric acid.