Cerebral perfusion and cognitive impairment in patients with vascular dementia

In the article results of the own investigation of cerebral perfusion in patients with different forms of vascular dementia are quoted. The investigation embraces the patients with different variants of clinical course of vascular dementia, including it's mixed (vascular-neurodegenerative) forms. Perfusion evaluation has performed by single-photon emission tomography (SPECT) with contrast strengthening. All patients were evaluated by complex neuropsychological scales. Basing on comparison of Cnnical data, neuropsychological measures and cerebral perfusion, the patterns of cognitive disorders in the case of different hypoperfusion zones were marked. The significance of inadequate blood supply even without structural changes in the manifestation of cognitive decline was demonstrated. Single-photon emission computer tomography allows to prognose the cognitive impairment progression in the dynamic evaluation.