Environmental levels of oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards – implications for the risk of an oseltamivir resistant influenza pandemic

Josef Järhult,Shaman Muradrasoli,John Wahlgren,Hanna Söderström,Goran Orozovic,Gunnar Gunnarsson,Caroline Bröjer,Neus Latorre-Margalef,Jerker Fick,Roman Grabic,Johan Lennerstrand,Jonas Waldenström,Åke Lundkvist,Björn Olsen

Environmental levels of oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards – implications for the risk of an oseltamivir resistant influenza pandemic

2011

Josef Järhult
Shaman Muradrasoli
John Wahlgren
Hanna Söderström
Goran Orozovic
Gunnar Gunnarsson
Caroline Bröjer
Neus Latorre-Margalef
Jerker Fick
Roman Grabic
Johan Lennerstrand
Jonas Waldenström
Åke Lundkvist
Björn Olsen

Resistance in influenza is a growing problem. Oseltamivir carboxylate (OC), the active substance of the most widely used antiviral drug oseltamivir (Tamiflu ®), is poorly degraded in sewage treatme ...

Keywords:

Oseltamivir
Antiviral drug
Influenza A (H1N1) virus
Oseltamivir carboxylate
Pandemic
Microbiology
Resistance mutation
Virology
Biology
influenza pandemic
oseltamivir resistant

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