A Clinical Study on the Effects and Mechanism of Xuebijing Injection () in Severe Pneumonia Patients

Objective To observe the effects of Xuebijing Injection ( ) in patients with severe pneumonia, and to explore the mechanism. Methods Eighty cases of severe pneumonia are randomly assigned to the Xuebijing treatment (forty cases) and the control group (forty cases), with the same routine therapy provided in both groups. Clinical effective rates, inflammatory factors and organ function were observed in both groups. Results The effective rate was higher in Xuebijing group than that of the control group (80.0% vs. 67.5%, P Conclusion Xuebijing Injection may show a protective effect in patients with severe pneumonia. The mechanism is possibly with the decreased secretion of TNF-α, IL-6, and IL-8.