Enzymatic activity of rat integument under the combined effect of external beta radiation and heat. [/sup 85/Kr; 36/sup 0/C]

It is interesting to investigate the manifestations of combined radiation lesions induced by external ..beta.. irradiation of the organism at high ambient temperature in view of the fact that such forms of extreme factors are encountered in some occupations. Evaluation of changes in some biochemical indices, including activity of tissular enzymes, is an important factor in studies of levels of various parameters characterizing the postradiation condition of the object under study. However, there are no data in the literature as yet concerning the behavior of enzymatic systems exposed to beta and thermal loads. For this reason, our objective here was to analyze the fluctuations in activity of two key enzymes of energy metabolism, ATPase and creatine kinase, in response to external ..beta.. irradiation (/sup 85/Kr) of an organism in a state of heat stress. We selected integumental tissue as the activity substrate due to the low penetration of /sup 85/Kr ..beta.. particles.