Utilization of DmbNHNH2 in the synthesis of amino-substituted 4-((3,5-diamino-1H-pyrazol-4-yl)diazenyl)phenols

Abstract (2,4-Dimethoxybenzyl)hydrazine (DmbNHNH 2 ) was utilized in the synthesis of Dmb-protected 4-((3,5-diamino-1 H -pyrazol-4-yl)diazenyl)phenols. This unambiguous protection of the pyrazole endocyclic nitrogen atom enabled the preparation of amino-substituted 4-((3,5-diamino-1 H -pyrazol-4yl)diazenyl)phenols that were inaccessible through direct substitution. The Boc group could be selectively cleaved in the presence of the Dmb group.