The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia.

Maria I. Edilova,Jaclyn C. Law,Safoura Zangiabadi,Kenneth Ting,Achire N. Mbanwi,Andrea Arruda,David Uehling,Methvin Isaac,Michael Prakesch,Rima Al-awar,Mark D. Minden,Ali A. Abdul-Sater,Tania H. Watts

The PKN1- TRAF1 signaling axis as a potential new target for chronic lymphocytic leukemia.

2021

Maria I. Edilova
Jaclyn C. Law
Safoura Zangiabadi
Kenneth Ting
Achire N. Mbanwi
Andrea Arruda
David Uehling
Methvin Isaac
Michael Prakesch
Rima Al-awar
Mark D. Minden
Ali A. Abdul-Sater
Tania H. Watts

TRAF1 is a pro-survival adaptor molecule in TNFR superfamily (TNFRSF) signaling. TRAF1 is overexpressed in many B cell cancers including refractory chronic lymphocytic leukemia (CLL). Little has be...

Keywords:

TRAF1
tnfr superfamily
Cancer research
Refractory Chronic Lymphocytic Leukemia
B cell
Protein kinase N1
adaptor molecule
Chronic lymphocytic leukemia
Medicine

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