Conscious sedation with midazolam in a dental patient with a spastic nerve/muscle disorder--a case report.

Abstract A case is presented in which intravenous midazolam was titrated to sedate a patient with a spastic nerve/muscle disorder during a post and crown preparation procedure. The patient, a 29-year-old woman with uncontrolled limb and body movements, was given midazolam in small incremental doses, not exceeding 0.5mg, at approximate intervals of 10 minutes after receiving a bolus dose of 0.75mg at the start of the procedure. The 0.5mg doses were given every time limb/body movements increased. The total dose of 0.1mg/kg, often given as a bolus for sedation in dentistry, was not exceeded during the procedure. No adverse effects were observed and the patient remained well sedated and cooperative during the entire procedure which was completed to the full satisfaction of all involved.