Relations between non-high-density lipoprotein cholesterol and coronary in-stent restenosis, deterioration of atherosclerotic plaques

Objective To study the relationships between non-high-density lipoprotein cholesterol and coronary in-stent restenosis,deterioration of atherosclerotic plaques.Methods The clinical data of 226 patients with coronary heart disease,who were treated by percutaneous coronary intervention (PCI),were sunmarized.After 12 months,the patients were reviewed by the coronary angiography,and they were divided into two groups:lesions progress group(coronary in-stent restenosis and deterioration of atherosclerotic plaques),no lesions progress group(no coronary in-stent restenosis or deterioration of atherosclerotic plaques).Results Among all the 226 patients,54 cases were diagnosed as coronary in-stent restenosis and deterioration of atherosclerotic plaques,172 cases without lesions progress.There were significant differences in total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),and non-high-density lipoprotein cholesterol (non-HDL-C) between the two groups.Conclusions TC,LDL-C,non-HDL-C may be important risk factors for the coronary stent restenosis after PCI,but the predictive value of non-HDL-C is superior to TC or LDL-C. Key words: Low-density lipoprotein cholesterol ;  Non-high-density lipoprotein cholesterol ;  Coronary atherosclerosis;  Coronary in-stent restenosis