Isolation, inhibitory spectrum and properties of bacteriocin like antimicrobial compound produced by B. cereus strain 06 isolated from soil

Antidiarrhoeagenic activities of 10 ethnomedicial plants extracts were evaluated against 4 bacterial strains, Escherichia coli, Vibro cholerae, Shigella dysentariae, Salmonella enterica. Plants were collected from a quiet Oban Community in South East Nigeria and the enthnobotanical data gathered. Solvent (methanol, ethanol diethyl ether) extracts obtained by Sohxlet were challenged with clinical isolates using paper disc diffusion method. The results indicated that 80% of the plants examined exhibited antidiarrhoeagenic activity against one or more of the tested organisms. Ethanolic extracts of Azadirachta indica and Dracaena manni were most active. Significant antidiarrhoeagenic effects expressed as MIC/MBC of extracts against all test organisms were observed with ethanolic extracts of Newbouldia laevis and may be associated with the high solubility of their phytochemicals. Generally, the potentials of these plants to produce antidiarrhoegonic components that can be useful for many applications are great and must be better explored. Key words: Antidiarrhoeaganic activity, medicinal plants, minimum inhibitory concentration (MIC), minimal bacterial concentration (MBC.)