Magnetic resonance imaging characteristics of multiple sclerosis plaques imaged with two-dimensional and three-dimensional Fourier transform techniques at low and mid field strengths.

: A total of 58 multiple sclerosis lesions from 16 patients were used to characterize the performance of a low field system for the detection of edematous (e.g., water-elevating) brain lesions. Contrast, signal-to-noise, and their product (signal difference to noise) were measured for two-dimensional and three-dimensional Fourier transform techniques at low field strength (640 G) and compared to two-dimensional sequences at mid field strength (3,500 G). The results showed numerically that low-field strength magnetic resonance imaging can reliably detect multiple sclerosis lesions, and, by extension, other water-elevating lesions, although with lower confidence levels.