Synthesis and Antimicrobial Activity of Isoxazoles

Isoxazoles have been prepared by the reaction of various 3-Carboxamido-(substitutedbenzothiazole- 2yl)-propane-2-one and hydroxylamine hydrochloride. The starting compound substituted 2–amino benthiazoles were prepared from various substituted amines via substituted phenyl thiourea. The structures of the compounds have been confirmed by elemental analysis and spectral analysis. The antibacterial activity of the compounds has also been screened against pathogenic organisms.