¿Asma o amiloidosis laríngea? Comunicación de un caso y revisión de la literatura

The laryngeal amyloidosis is an uncommon disease accounting for 1% of all benign lesions of larynx. The commonest symptom is the dysphonia, sometimes accompanied by stridor, laryngeal globe sensation, dysphagia and, in rare occasions, cough, dyspnea and hemoptisis, specially when the traqueobronquial tree is also affected. This paper describes the case of a 30 year old female patient, whose main symptoms were progressive dysphonia and dyspnea, admitted at allergy service to discard asthma. The respiratory function tests showed obstruction in the medium and small caliber ways without reversibility with salbutamol. Biopsies of ventricular band, vocal cord and aritenoides dyed with positive Congo red for amyloid tissue, established the laryngeal amyloidosis diagnosis. The complementary studies to discard amyloid tissue in the remaining traqueobronquial tree were negative. Dyspnea had characteristics of laryngeal origin, caused by a pulmonary ventilation disorder provoked by the difficult arrival of air to alveoli, which caused the decreased partial tension of oxygen and CO2.