A kind of preparation method of unformed cefditoren

The invention discloses a kind of preparation methods of unformed cefditoren, by cefditoren dissolution of crystals in organic solvent, it is unformed that rapid concentration obtains cefditoren, or is concentrated into after small size and is added dropwise in second of organic solvent that cefditoren is precipitated is unformed.Target product is detected through XPRD, is unformed peak type.The unformed dissolubility for increasing cefditoren of the cefditoren that the present invention is prepared is more advantageous to the bioavilability for improving pharmaceutical preparation.Preparation method disclosed by the invention, mild condition, process stabilizing are easily operated.