BIOLOGICAL PROPERTIES OF ANTISENSE OLIGONUCLEOTIDES CONJUGATED TO DIFFERENT HIGH-MOLECULAR MASS POLY(ETHYLEN GLYCOLS)

Gian Maria Bonora,E. M. Ivanova,N. Komarova,D. Pishiniyi,P. E. Vorobjev,V. F. Zarytova,S. Zaramella,Francesco M. Veronese

BIOLOGICAL PROPERTIES OF ANTISENSE OLIGONUCLEOTIDES CONJUGATED TO DIFFERENT HIGH-MOLECULAR MASS POLY(ETHYLEN GLYCOLS)

1999

Gian Maria Bonora
E. M. Ivanova
N. Komarova
D. Pishiniyi
P. E. Vorobjev
V. F. Zarytova
S. Zaramella
Francesco M. Veronese

Abstract The effect of the different structures of high-molecular weight poly(ethylen glycol) chains on the biological properties of the conjugated antisense oligonucleotide has been investigated and compared.

Keywords:

Oligonucleotide
Biochemistry
Conjugated system
Sense (molecular biology)
Molecular mass
Chemistry
Organic chemistry
Molecular biology
antisense oligonucleotide
antisense oligonucleotides
biological property
high molecular mass

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