The ACE gene I/D polymorphism does not affect the susceptibility to or prognosis of PBC.

Primary biliary cirrhosis (PBC) is a chronic autoimmune inflammatory liver disease characterized by the presence of an intrahepatic mononuclear cell infiltrate, as well as circulating auto-antibodies (1, 2). The occurrence of hepatic angiogenesis in the liver of PBC patients is a novel finding (3). The excessive accumulation of inflammatory infiltrates, together with the accumulation of extracelluTurk J Gastroenterol 2008; 19 (4): 250-253