Síndrome Sapho: reporte de caso

espanolEl sindrome SAPHO es una enfermedad inflamatoria de origen multifactorial que incluye una asociacion entre manifestaciones dermatologicas y osteoarticulares. La presencia de osteitis e hiperostosis definen la enfermedad. No existe un tratamiento estandar, pero se usan AINES como primera linea. Se presenta el caso de un varon de 18 anos con acne severo en dorso, pecho, barbilla y zona retroauricular, asociado a fiebre alta y placas eritematosas en ambas piernas. La gammagrafia presenta hipercaptacion en tibia derecha, con relacion a osteitis no infecciosa. Tuvo evolucion favorable con antibioticos y corticoide oral. EnglishSAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is a multifactorial inflammatory condition that includes an association between dermatological and bone and joint manifestations. The presence of osteitis and hyperostosis define this disease. There is no standard therapy for SAPHO syndrome, but NSAIDs are used as first line. We present the case of an 18-year-old male subject with severe acne on his back, chest, chin, and the retroauricular area, being this associated to high fever and erythematous plaques in both legs. The bone scan showed right leg hyper-uptake, related to non-infectious osteitis. The patient did well with antibiotics and oral steroids.