Biotemplated multichannel mesoporous bioactive glass microtubes as a drug carrier

Abstract Multichannel mesoporous bioactive glass (MBG) microtubes were synthesized using Pluronic P123 and wool sponges as templates. The fine one-dimensional multichannel structures of the biological templates were faithfully duplicated. The wool sponges not only created pores but also helped increase the growth rate of hydroxycarbonate apatite in simulated body fluid (SBF). The biocompatibilities were also evaluated by culturing the MC3T3-E1 cells on the mesoporous bioactive glass microtubes. The MBG microtubes exhibited delicate multichannel tubular structures, bioactivities, biocompatibilities and the capability for sustained drug delivery. The data provided evidence that the material had excellent potential for applications in the fields of tissue engineering and drug storage.