Особенности течения остеопороза у пациентов с хронической обструктивной болезнью легких

The aim of this study was to analyze the course of osteoporosis in elderly females with pulmonary diseases. Methods . The study involved females with postmenopausal osteoporosis who did not receive regular treatment with oral steroids. All patients underwent spirometry before and after inhalation of a bronchodilator, bone densitometry with assessment of bone mineral density (BMD) and T-score at the proximal thigh, the lumbal spine and the one third distal forearm. FRAX risk assessment score was also used. Results . We examined 79 patients (mean age, 66.9 ± 1.7 years). Female patients with chronic obstructive pulmonary disease (COPD) had significantly more frequent forearm fractures, significantly lower FEV1, BMD at the forearm, and T-score at the forearm compared to patients with asthma and patients without obstructive pulmonary diseases. Conclusions. COPD contributes to more severe course of postmenopausal osteoporosis.