Benzodiazepine Structure versus Reactivity with EMIT Oxazepam Antibody

AbstractOver 50 different benzodiazepines were analyzed by EMIT (Enzyme Multiplied Immunoassay Technique) at several different concentrations. An attempt is made to relate structural differences to the affinity of the compounds for the EMIT oxazepam antibody. The effects of substituent placement on the oxazepam molecule are studied.