Sentinel Lymph Node Biopsy in Prostatic Cancer

The identification of lymph drainage has significant clinical importance for tumor spread in prostatic cancer. Pelvic lymph node metastases indicate a poor prognosis for patients with clinically localized prostate cancer. The prognosis depends on nodal cancer volume (1), extracapsular extension (2), and the number of prostatic nodes affected (3). It is not clear whether the more valuable prognostic factor is the diameter of the largest metastases, or the total number of positive lymph nodes (4).