Clinical Effectiveness of Transcervical Polyp Resection in Women with Endometrial Polyps: Randomized Controlled Trial

Abstract Study Objective To estimate the clinical effectiveness of transcervical resection of endometrial polyps. Design Randomized controlled trial (Canadian Task Force classification I). Setting University teaching hospital. Patients One hundred fifty premenopausal women with endometrial polyps. Interventions Either transcervical resection of the polyp or observation for 6 months. Measurements and Main Results There was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11–1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p Conclusion Transcervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women.