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Germline variant FGFR4 p.G388R exposes a membrane-proximal STAT3 binding site
2015
A gain-of-function effect of the cancer-associated rs351855 single-nucleotide polymorphism encoding the FGFR4 Arg388 allele in humans.
Keywords:
- Germline
- Exon
- Peptide sequence
- Binding site
- Genetics
- Cell membrane
- Polymorphism (computer science)
- Germline mutation
- Allele
- Biology
- Fibroblast growth factor receptor
- Tyrosine phosphorylation
- Fibroblast growth factor receptor 4
- Transmembrane protein
- Cell biology
- Cell surface receptor
- Signal transduction
- Cancer research
- Correction
- Source
- Cite
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