The Role of Polysorbate 80 and HPβCD at the Air-Water Interface of IgG Solutions

Tim Serno,Elisabeth Hartl,Ahmed Besheer,R. Miller,Gerhard Winter

The Role of Polysorbate 80 and HPβCD at the Air-Water Interface of IgG Solutions

2013

Tim Serno
Elisabeth Hartl
Ahmed Besheer
R. Miller
Gerhard Winter

Purpose To test the hypothesis of surface displacement as the underlying mechanism for IgG stabilization by polysorbates and HPβCD against surface-induced aggregation.

Keywords:

Polysorbate 80
Polysorbates
Polysorbate
Chemistry
Biochemistry
Chromatography
Surface tension
air water interface
surface displacement
Beta-Cyclodextrins
protein stability

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