Imaging Neural Activity Using Thy1-GCaMP Transgenic Mice

Qian Chen,1 Joseph Cichon,3,10 Wenting Wang,1,10 Li Qiu,4 Seok-Jin R. Lee,4 Nolan R. Campbell,1 Nicholas DeStefino,6 Michael J. Goard,2 Zhanyan Fu,1,5 Ryohei Yasuda,4 Loren L. Looger,7 Benjamin R. Arenkiel,8 Wen-Biao Gan,3 and Guoping Feng1,9,* 1McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences 2Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences Massachusetts Institute of Technology, Cambridge, MA 02139, USA 3Molecular Neurobiology Program, Skirball Institute, Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY 10016, USA 4Department of Neurobiology 5Department of Psychiatry and Behavioral Science Duke University Medical Center, Durham, NC 27710, USA 6MD-PhD Program, Harvard Medical School, Boston, MA 02115, USA 7Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA 20147, USA 8Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA 9Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA 02142, USA 10These authors contributed equally to this work *Correspondence: fengg@mit.edu http://dx.doi.org/10.1016/j.neuron.2012.07.011