How About P300 in Patients with Depression in China: Review of Results from Some Chinese Meta- Analysis

The depression are a common mental disorders in China. It's morbidity is about 4. 0/100, which influence Chinese people's mental health. The Chinese psychiatrists carry out many studies about depression in aetiology，therapeutics，prophylaxis and rehabilitation. The study of P 300 in patients with depression are one of those studies, and also generated some studies about relationship between P300 and depression. These studies include : (1) features of depression patients, (2) effects of antidepressants on P300 in patients with depression, (3) relationship between P300 and depression symptoms, (4) relationship between P300 and cognitive impairment, (5) treatment effective prediction role of P300 in patients with depression. (6) P300 aid in the differential diagnosis of subtype of depression. These results will be reviewed and assessed in our review. Major depressive disorder is a serious mental disorder that profoundly affects an individual's quality of life. Although the aetiology underlying this disorder remain unclear, an increasing attention has been focused on the pathophysiological changes, regardless of etiology or outcome, which are associated with depression (Yang et al., 2015). The existence of such a link is indeed conducive to the study of the etiology of depression and the initiation of therapeutic. P300 also was studied widely in depression as a index of cognitive function, because most of patients with depression often are company with cognitive impairment. P300 waveform is the most widely used component of event-related brain potential (ERP), which is related to cognitive information processing, including working memory, attention and executive function. As an electrophysiological indicator of cognitive activity, P300 is non-invasive, inexpensive, convenient, and free of cultural and educational bias. Because of its high temporal resolution, P300 is more sensitive to cognitive changes than traditional neuropsychological tests and can provide insight into cognitive processes.