A case of fatal pulmonary embolism raising questions about the dosing regimen for dalteparin in the very obese

discussed in their review, the mechanism of action of lenalidomide against target cells with del 5q is yet to be fully characterised. It may relate to the inhibition of angiogenesis or modulation of cell survival proteins encoded by genes located on chromosome 5q-. Based on this case, one further potential mechanism for consideration is through suppression of T-cell function (or other pathway) targeted by immunosuppressive agents, such as ciclosporin and T-cell specific serotherapy.