Nachweis des mutierten ras-Onkogens in Pankreas-karzinomen : Verbesserung der diagnostischen Möglichkeiten mit Hilfe molekularbiologischer Techniken ?

: C-Ki-ras oncogenes have been detected by polymerase chain reaction in the majority of pancreatic carcinomas. The biological role of ras oncogenes in pancreatic carcinogenesis is unknown. This review summarizes the current knowledge of ras oncogenes in pancreatic carcinomas, the different techniques for oncogenes and their possible diagnostic value.