A viral protein promotes host SAMS1 activity and ethylene production for the benefit of virus infection

Rice provides food for billions of people all over the world, but diseases caused by plant-infecting viruses cause serious risks to the production of rice. As a result, there is an urgent demand for developing new and impactful ways to help defend rice plants from harmful viruses. Toward this goal, it will be important to better understand how viruses actually cause diseases in plants. Plants make chemicals known as hormones to control their own development, and hormone production is often disturbed when viruses infect rice plants. Many viruses cause infected plants to make more of a gaseous hormone called ethylene, which benefits the viruses. Yet, it is still not known how virus infection induces the production of more ethylene. Zhao, Hong et al. have exposed rice plants to infection with a virus called rice dwarf virus. Infected plants made more ethylene than normal, which did indeed help the virus to infect. Further experiments then showed that an enzyme that makes one of the building blocks needed to produce ethylene became more active after infection with this virus. Next, Zhao, Hong et al. engineered rice plants to make more or less of this building block – which is known as S-adenosyl-L-methionine or SAM for short. Plants with too much SAM were less able to defend themselves against the virus, while plants that lacked SAM were better able to fight off viral infection. Zhao, Hong et al. suggest that engineering rice plants to make less of the SAM-producing enzyme could make them more resistant to viruses. Further work will also be needed to find out why ethylene benefits viral infection, and to confirm whether ethylene also performs similar roles when rice is infected with other viruses.