Familial hemophagocytic lymphohistiocytosis: Improved neurodevelopmental outcome after bone marrow transplantation
1998
Abstract A child with familial hemophagocytic lymphohistiocytosis (HLH) underwent allogeneic bone marrow transplantation (BMT) at age 5 months. At that time he showed delayed psychomotor development, and computed tomography revealed diffuse calcification. After BMT, a gradual neurodevelopmental normalization was observed. The potential ability of BMT to reverse neurodevelopmental deterioration in HLH should be considered. (J Pediatr 1998;133:126-8)
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