Elements of a specific binding pair with a chemical group covalently bound in the binding site; production and selection of them.

Repertoires FIRST MEMBERS OF PAIRS OF UNION SPECIFIED (SBP) wherein each first member of SBP has one unit QUIMICA covalently linked to an amino acid residue WITHIN THE SITE LINK YOU CAN DO AND SEE THE SURFACE OF A BODY AS A bacteriophage. Methods for producing such REPERTOIRES may consist in taking a population of nucleic acid molecules encoding WHERE codon encoding an amino MODIFIED SELECTIVE or preferentially enters the region encoding the binding, for example by a MUTATION OR STRUCTURE GENES. The first member of SBP (EJ. ANTIBODY) WHERE THE UNION TO A SECOND MEMBER SBP (EJ. Antigen) IS RAISED IN OR DEPENDENT ON THE PRESENCE OF CHEMICAL UNIT IN PLACE OF LINK can be selected repertoires.