Human umbilical cord mesenchymal stem cells-derived exosomes transfers microRNA-19a to protect cardiomyocytes from acute myocardial infarction by targeting SOX6.

Lin Huang,Lu Yang,Yin Ding,Xinghua Jiang,Zhen Xia,Zhigang You

Human umbilical cord mesenchymal stem cells-derived exosomes transfers microRNA-19a to protect cardiomyocytes from acute myocardial infarction by targeting SOX6.

2020

Lin Huang
Lu Yang
Yin Ding
Xinghua Jiang
Zhen Xia
Zhigang You

ABSTRACTExosomes secreted by human umbilical cord mesenchymal stem cells (hucMSCs) protect cardiomyocytes from anoxia-reoxygenation injury. But the mechanism of hucMSC-exo-microRNA (miR)-19a in acu...

Keywords:

Microvesicles
Umbilical cord
Cell biology
microRNA
Biology
Myocardial infarction
Mesenchymal stem cell
Cancer research
Downregulation and upregulation
Apoptosis
Western blot
Protein kinase B
Gene knockdown

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