Clinical value of ~(11)C-MET PET-CT in diagnosis of breast cancer

Objective:The aim of this study was to evaluate the clinical role of 11C-methionine(MET) PET-CT in detection of breast cancer.Methods:11C-MET PET-CT scans were performed on 45 patients with suspected breast tumor.The final diagnosis was obtained by pathologic finding from surgery or biopsy.Results:The overall sensitivity,specificity and accuracy of 11C-MET PET-CT for detecting primary breast cancer were 100%(44/44),80%(12/15) and 94.9%(56/59),respectively.Conclusion:11C-MET PET-CT is a valuable imaging tool to early detect breast cancer.【