P616 Impact of psychological factors in relapse of Crohn's disease

Results: In total, 6,863 incident cases were identified. The overall mean annual incidence rate for all MC cases was 3.2 per 100,000 person years. We found 3,724 cases of CC (75.6% females) and 2,385 cases of LC (70.5% females) with an overall mean annual incidence rate of 1.7 and 1.1 per 100,000 person years, respectively. Remaining 754 cases were described as uMC. From 2000 to 2012, the incidence rates increased significantly from 1.2 to 2.5 per 100,000 person years (p < 0.001) in CC and from 0.3 to 2.3 per 100,000 person years (p < 0.001) in LC (see Figure). Compared to CC, the incidence rate of LC increased significantly more over time. The total number of MC cases per 1,000 colonoscopies increased as well, from 2.3 to 2.9 between 2004 and 2011. For both CC and LC the median age at diagnosis was 61 years. Females above 65 years of age had a 3.6 and 3.3 times increased risk of CC and LC, respectively, compared to those below 65 years.