Chapter 6:Emerging Synthetic Technologies

In this chapter the author seeks to place the current state of the art in synthetic technologies into a historical context. The challenges remaining to synthetic chemists in order to fully explore chemical space are outlined. Finally, emerging approaches to these challenges are reviewed from the cutting edge areas of template-guided systems and knowledge-based iterative approaches including dynamic combinatorial chemistry, click chemistry, siRNA, directed assembly using DNA and iterative microfluidic approaches.