Sa1098 The Association Between Socioeconomic Status and Quality of Life of Diabetic Patients With Constipation

by Los Angeles (LA) classification were evaluated. Results: Seventy patients (48%) were partial responder to PPI therapy. These patients reported significantly lower scores in the mental health component summary of SF-8, PSQI and HADS including anxiety and depression than responder to PPI. Anxious or depressive state patients (HADS total score>11) are 69% in partial responder to PPI, whereas 31% in responder to PPI (P=0.006). PPI daily dose and LA classification were also significant factors that associated with the response to PPI. Conclusion: Partial responder to PPI showed decreased mental HRQoL. Persistent and troublesome reflux symptoms on PPI therapy seemed to be important factors affecting mental HRQoL including anxiety, depression and sleep disturbance in Japanese GERD patients. The scores of each questionnaire