The A−336C Insulin-Like Growth Factor Binding Protein-3 Promoter Polymorphism Is Not a Modulator of Breast Cancer Risk in Caucasian Women

Insulin-like growth factors (IGF) play an important role in the proliferation and apoptosis of several cell types and may therefore be associated with the risk of malignant transformation ([1][1]). IGF binding protein-3 (IGFBP-3) is the most common binding protein for IGF-I in serum. High levels of